Customization: | Available |
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After-sales Service: | One Year Free Parts |
Warranty: | One Year |
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Systems Description
BIOF-S fermentation system mainly includes tank body, pipe valve, air filtration system, temperature automatic control system, speed control system, pH online detection and automatic control system, DO online monitoring and automatic control system, automatic defoaming, automatic feeding, PLC centralized Control system, host computer control system, etc. Oil-free silent air compressor, automatic electric steam generator.
Design pressure 0.3 Mpa; body material: 316L stainless steel, jacket 304 stainless steel; with special sampling valve for fermentation tank, bottom discharge valve, with side large viewing angle mirror, 12V safety Philips lighting, with temperature, pH, DO , Defoaming port, acid and alkali replenishment port, inoculation port, replenishment port, air inlet, exhaust port, seed transfer port, liquid level electrode, defoaming electrode, etc.; internal polishing accuracy Ra0.4, external polishing accuracy Ra0. 6. All welds are firm, neat and beautiful.
Technical Specifications
Item name |
Specifications |
Model |
BIOF-S |
Capacity |
10 ~ 20000 liters |
Tank |
Sterilization in place, design pressure 0.3 Mpa; Body material: 316L stainless steel, jacket 304 stainless steel; With special sampling valve for fermentation tank, bottom discharge valve, with side Large-view mirror, 12V safety Philips lighting, with Temperature, pH, DO, defoaming port, acid and alkali replenishment port, inoculation port, feed port, air inlet, exhaust port, seed transfer port, liquid level electrode, defoaming electrode, etc.; Internal polishing accuracy Ra0.4, external polishing accuracy is Ra0.6, and all welds are firm, neat and beautiful. |
Mixing system |
Servo motor, speed governor; continuous and stable, adjustable; control accuracy ±1% Top-type mechanical stirring system, adopts special 316L stainless steel for stirring shaft, AD mechanical seal (a special mechanical seal system that can meet higher fermentation requirements); Adopts adjustable 2-stage 6-inclined blade stirring paddle, 1-stage compression type high-efficiency Bubble paddle, 4-level detachable baffle; |
Intake & filtration |
Deep ventilation is adopted, with the maximum ventilation 1.5VVM; Primary filtration, 0.01μm precision sterilization filter, fine filter selection of high-quality products, to ensure safety and independent sterilization, greatly extending the service life; annular gas distribution at the bottom Device |
pH control |
Electrode: Mettler high temperature resistant glass electrode Control range: 2-12pH, display range: 0-14pH, Control accuracy: ±0.02pH, resolution: 0.01pH; Control: Intelligent PID control, abnormal pH value alarm, segment control, data can be uploaded to the host computer |
DO2 control |
Electrode: Mettler high temperature resistant glass electrode Control range: 0-100%, display range: 0-200%, Control accuracy: ±5%, resolution: 0.1%; Control: Intelligent PID control, abnormal DO value alarm, data can be uploaded to the host computer |
Temperature Control System |
Electric heating, water cooling, circulating pump temperature control, air escape function and water cut, over-temperature protection function, with good heat exchange efficiency; Intelligent PID control not only ensures the rapidity of temperature control, but also realizes energy saving. Temperature control: cooling water temperature +5ºC-65ºC±0.2ºC, display temperature: 0-150ºC±0.1ºC Fermentation process sequence control (set according to fermentation time zone, temperature automatic variable control, at least 10 sections) |
Defoaming system |
Antifoaming agent: flow addition by peristaltic pump Highly sensitive defoaming electrode Control method: time and proportion automatic control |
Gas flow detection system |
Air intake method: bottom annular gas distributor (enlarged aperture to effectively prevent foreign matter obstruction), controlled air intake system Flow control: rotameter, Siemens module, MFC auto flow control is optional Air filtration: pre-main pre-filter, secondary air inlet filter (the filter can be sterilized independently). Fine filtration, the filter shell is made of 304 stainless steel, the filter element filtration effect can reach the sterile filtration level, the filter element material is hydrophobic polytetrafluoroethylene or other suitable materials, the sterilization filter has an online integrity test port, and each sterilization filter has an independent Online sterilization process. Pre-filter, filter housing is made of 304 stainless steel. Intake control: rotameter. The air intake pipeline has a diaphragm valve that can be manually opened and closed. Check device: There is a check device to prevent the valve from being sucked back by materials. Pressure display: displays the pressure of ventilation and sterilization process with an accuracy of 0.01MPa Drainage: The filter is designed with a drainage device and has measures to prevent back suction. Exhaust: The exhaust is manually controlled by a pneumatic diaphragm valve; the gas is filtered and discharged, and the filter shell is made of 304 stainless steel. Sterilization requirements: Filters, inlet and exhaust pipelines can be steam sterilized online Ventilation: Rotameter control, adjust and control the flow of each gas according to process requirements, the maximum ventilation flow is 2VVM. The air system consists of pre-filter, flow meter, air fine filter, diaphragm valve, and check valve. Steam filtration precision: 1um. |
* MFC Auto flow control |
Vogtlin mass flow controller: The mass flow controller is used to accurately control the air intake flow, and the air flow can be automatically adjusted according to the dissolved oxygen value. Maximum design flow is about 2VVM, and the control accuracy is ±0.5% |
Pressure detection system |
Direct-mounted pressure gauge Control method: Auto control Pressure gauge auxiliary display, control range: 0-0.4MPa, high temperature resistant and high-precision pressure sensor is used to accurately detect the fermentation tank pressure, the regulating valve automatically adjusts the tank pressure. Pressure measurement range: 0-0.35Mpa, ±0.3%, control accuracy :±0.5% |
Automatic feeding system |
PID automatic setting control fermentation process segmented control (according to fermentation time, automatic variable control of feeding, at least 10 segments) feeding amount curve analysis adding amount cumulative display record data storage Equipped with a complete replenishment system, the replenishment can be measured; Number of peristaltic pumps can be selected according to needs, and conventional configuration is four. The role of the peristaltic pump can be selected and set on the control interface, which makes the user more convenient and flexible in actual use. Equipped with specially designed replenishment pins to ensure the safe operation of replenishment. |
SIP system |
One-click fully automatic sterilization, including filters, tanks and pipelines. Sampling valve and discharge valve manual sterilization Sterilization temperature: 100-130ºC; |
* Can lid lifting |
Stainless steel guide rail, stepper motor |
* Tank weighing system |
The weighing module is used to accurately measure the fermentation liquid with an accuracy of up to 0.1% |
Transplant |
Can be transferred to the next level, using stainless steel valves and polished pipes; The rationality of the design ensures the safe realization of the transfer |
System equipped with valve pipeline |
Valve material: AISI 316L, the valve in contact with the material adopts imported diaphragm valve The pipeline is made of stainless steel with precision polished; argon gas shielded welding; meets GMP requirements The stainless steel table frame is used, and the bottom is installed with pulleys for easy movement |
* Automatic CIP System |
lye tank hot water tank Diaphragm pump CIP Outlet Pump CIP cleaning return pump liquid level sensor Temperature Sensor conductivity meter Manual butterfly valve Pneumatic Butterfly Valve Control cabinet |
key components
Part Name |
Brand |
Origin |
Remark |
pH electrode |
Hamilton/Mettler |
Switzerland |
Standard fitted |
DO electrode |
Hamilton/Mettler |
Switzerland |
Standard fitted |
pH signal transmission line |
Hamilton/Mettler |
Switzerland |
Standard fitted |
DO signal transmission line |
Hamilton/Mettler |
Switzerland |
Standard fitted |
touch screen |
MCGS |
Well-known domestic brands |
Standard fitted |
PLC |
Siemens |
Germany |
Standard fitted |
Thermostatic water pump |
WILO |
German brand |
Standard fitted |
Electric machine |
SEW |
Germany |
Standard fitted |
Frequency converter |
BOSCH |
Germany |
Standard fitted |
controlling software |
Bioreactek™ |
China |
Standard fitted |
The electromagnetic valve |
Sanlixin/Julang |
Zhejiang/Shanghai |
Standard fitted |
Pneumatic diaphragm valve, pneumatic angle seat valve, manual diaphragm valve, proportional solenoid valve |
Burkert/Gemi/DK |
GermanyChina |
Standard fitted |
Rotameter |
Chengfeng |
China |
Standard fitted |
Filter cartridge |
|
Shanghai |
Standard fitted |
Pressure sensor |
Burkert |
Germany |
Standard fitted |
key components
Part Name |
Brand |
Origin |
Remark |
pH electrode |
Hamilton/Mettler |
Switzerland |
Standard fitted |
DO electrode |
Hamilton/Mettler |
Switzerland |
Standard fitted |
pH signal transmission line |
Hamilton/Mettler |
Switzerland |
Standard fitted |
DO signal transmission line |
Hamilton/Mettler |
Switzerland |
Standard fitted |
touch screen |
MCGS |
Well-known domestic brands |
Standard fitted |
PLC |
Siemens |
Germany |
Standard fitted |
Thermostatic water pump |
WILO |
German brand |
Standard fitted |
Electric machine |
SEW |
Germany |
Standard fitted |
Frequency converter |
BOSCH |
Germany |
Standard fitted |
controlling software |
Bioreactek™ |
China |
Standard fitted |
The electromagnetic valve |
Sanlixin/Julang |
Zhejiang/Shanghai |
Standard fitted |
Pneumatic diaphragm valve, pneumatic angle seat valve, manual diaphragm valve, proportional solenoid valve |
Burkert/Gemi/DK |
GermanyChina |
Standard fitted |
Rotameter |
Chengfeng |
China |
Standard fitted |
Filter cartridge |
|
Shanghai |
Standard fitted |
Pressure sensor |
Burkert |
Germany |
Standard fitted |