Stainless Steel Bioreactor Fermenter 10L~100L

• After-sales Service: One Year Free Parts
• Warranty: One Year
• Function: Reaction Pressure Vessel
• Application: Liquid
• Material: Stainless Steel
• Pressure: 0-0.4MPa
• Model NO.: BIOF-S Series
• Pressure Level: Low Pressure (0.1MPa≤p<1.6MPa)
• Condition: New
• Speed Range: 50~600rpm ±1%
• Transport Package: Plywood Packing
• Specification: 10L~100L
• Trademark: Xiangyi
• Origin: China
• Production Capacity: 100 PCS/Month

Product Description

 

BIOF Series Stainless Steel Fermenter
10L, 20L, 30L, 50L, 100L


Systems Description
This fermentation system mainly includes tank body, pipe valve, air filtration system, temperature automatic control system, speed control system, pH online detection and automatic control system, DO online monitoring and automatic control system, automatic defoaming, automatic feeding, PLC centralized Control system, host computer control system, etc. Oil-free silent air compressor, automatic electric steam generator.

Design pressure 0.3 Mpa; body material: 316L stainless steel, jacket 304 stainless steel; with special sampling valve for fermentation tank, bottom discharge valve, with side large viewing angle mirror, 12V safety Philips lighting, with temperature, pH, DO , Defoaming port, acid and alkali replenishment port, inoculation port, replenishment port, air inlet, exhaust port, seed transfer port, liquid level electrode, defoaming electrode, etc.; internal polishing accuracy Ra0.4, external polishing accuracy Ra0. 6. All welds are firm, neat and beautiful.
 
Technical Specifications

No.	Item name	Specifications
	Model	BIOF-S10L	BIOF-S20L	BIOF-S30L	BIOF-S50L	BIOF-S100L
1.	Tank capacity	10L	20L	30L	50L	100L
	Tank size	Φ180×400mm	Φ230×500mm	Φ273×550mm	Φ300×650mm	Φ400×750mm
	Jacket size	Φ220×3mm	Φ273×3mm	Φ325×3mm	Φ350×3mm	Φ450×4mm
	Tank	Sterilization in place, design pressure 0.3 Mpa; Body material: 316L stainless steel, jacket 304 stainless steel; With special sampling valve for fermentation tank, bottom discharge valve, with side Large-view mirror, 12V safety Philips lighting, with Temperature, pH, DO, defoaming port, acid and alkali replenishment port, inoculation port, feed port, air inlet, exhaust port, seed transfer port, liquid level electrode, defoaming electrode, etc.; Internal polishing accuracy Ra0.4, external polishing accuracy is Ra0.6, and all welds are firm, neat and beautiful.
2.	Motor power	0.4kw	0.75kw	1.0kw	1.0kw	1.5kw
	Speed range	50~600rpm ±1%	50~600rpm ±1%	50~600rpm ±1%	50~600rpm ±1%	50~600rpm ±1%
	Mixing system	Servo motor, speed governor; continuous and stable, adjustable; control accuracy ±1% Top-type mechanical stirring system, adopts special 316L stainless steel for stirring shaft, AD mechanical seal (a special mechanical seal system that can meet higher fermentation requirements); Adopts adjustable 2-stage 6-inclined blade stirring paddle, 1-stage compression type high-efficiency Bubble paddle, 4-level detachable baffle;
3.	Intake & filtration	Deep ventilation is adopted, with the maximum ventilation 1.5VVM; Primary filtration, 0.01μm precision sterilization filter, fine filter selection of high-quality products, to ensure safety and independent sterilization, greatly extending the service life; annular gas distribution at the bottom Device
4.	pH control	Electrode: Mettler high temperature resistant glass electrode Control range: 2-12pH, display range: 0-14pH, Control accuracy: ±0.02pH, resolution: 0.01pH; Control: Intelligent PID control, abnormal pH value alarm, segment control, data can be uploaded to the host computer
5.	DO2 control	Electrode: Mettler high temperature resistant glass electrode Control range: 0-100%, display range: 0-200%, Control accuracy: ±5%, resolution: 0.1%; Control: Intelligent PID control, abnormal DO value alarm, data can be uploaded to the host computer
6.	Temperature Control System	Electric heating, water cooling, circulating pump temperature control, air escape function and water cut, over-temperature protection function, with good heat exchange efficiency; Intelligent PID control not only ensures the rapidity of temperature control, but also realizes energy saving. Fermentation temperature control range: cooling water temperature +6~50ºC; accuracy: ±0.2ºC; resolution: 0.1ºC;
7.	Defoaming system	Antifoaming agent: flow addition by peristaltic pump Highly sensitive defoaming electrode Control method: time and proportion automatic control
8.	Flow detection system	Stainless steel flowmeter controls the intake air flow Control method: manual control
9.	Pressure detection system	Direct-mounted pressure gauge Range: 0-0.4MPa Control method: manual control
10.	Automatic feeding system	Equipped with a complete replenishment system, the replenishment can be measured; Number of peristaltic pumps can be selected according to needs, and the conventional configuration is four. The role of the peristaltic pump can be selected and set on the control interface, which makes the user more convenient and flexible in actual use. Equipped with specially designed replenishment pins to ensure the safe operation of replenishment.
11.	Sterilization system	Manual control, the sterilization method includes jacket heating, and steam sterilization in the tank at the same time; or the tank does not enter the steam and sterilizes only by jacket heating Sterilization temperature: 100-130ºC;
12.	Transplant	Can be transferred to the next level, using stainless steel valves and polished pipes; The rationality of the design ensures the safe realization of the transfer
13.	System equipped with valve pipeline	Valve material: AISI 316L, the valve in contact with the material adopts imported diaphragm valve The pipeline is made of stainless steel with precision polished; argon gas shielded welding; meets GMP requirements The stainless steel table frame is used, and the bottom is installed with pulleys for easy movement
14.	La-M controller & LF-Control control system	Siemens PLC programmable controller, advanced IoT touch screen, multi-touch operation Online display, control and editing of all parameters, historical data recording and export, support user customization, and can also be customized according to user requirements It can simultaneously detect and control the stirring speed, tank temperature, pH value, DO value, feeding, acid and alkali, defoaming, etc.; Each parameter has PID adjustment process display, such as set value, real-time value, PID set value, upper and lower limit value; The upper and lower limits of temperature, rotation speed, pH value, DO value can be set, and the limit alarm function is provided; Speed, temperature, pH value, DO value, replenishment, etc. can be set to automatic, manual and closed states; There is a complete feeding system, the peristaltic pump can periodically and quantitatively feed, the feeding can be measured, and the curve can be displayed; With the function of over-level alarm and automatic refilling, with the function of over-foam level alarm and automatic addition of defoamer; Equipped with the associated control of dissolved oxygen and speed, that is, the method of changing the speed to improve the dissolved oxygen concentration of the culture solution; Associated control of feeding and pH; Associated control of feeding and dissolved oxygen. Sterilization manual control, the sterilization method includes jacket heating, and steam sterilization in the tank at the same time; or the tank does not enter the steam and sterilizes only by jacket heating, sterilization temperature: 100-130ºC; The system has real-time display, data recording, data storage, data analysis (histogram, curve Line graphs and batch reports) output printing, password management, abnormal analysis and other functions and alarm functions; The historical data and curves of various parameters can be stored for many years (you must have a host computer to achieve); important The parameters are written into the database synchronously to prepare for data analysis at any time. The real-time data can be restored intact when the power is cut off and the machine is restarted; the full Chinese interface is provided with detailed help instructions. The parameters of each detection and control loop can be manually set and corrected online on the screen, temperature, PH, and DO sensors can be adjusted and adjusted, and the flow rate of each peristaltic pump can be calibrated; The system has self-adaptive and self-diagnostic capabilities; abnormal conditions can be automatically alarmed and protected according to customer settings. All alarm accidents can be recorded and consulted; Operation has a password protection function, the password is divided into operator and administrator level passwords; With automatic control and manual control switching.

key components

No.	Name	Description	Original
1	Tank	The material in contact with the liquid is 316L stainless steel; the rest is 304 stainless steel, precision-machined.	XIANGYI
2	Special sampling valve	QRF	XIANGYI
3	Machinery Seal	High-speed single-ended seal, 58U	Debao
4	Heater	Self-protection	QR
5	Stirring motor	Fermentation tank dedicated wide range, low noise, high temperature resistance, long life, constant torque speed regulation motor;	QR
6	Fermentation system software	Automatic fermentation system control software	XIANGYI
7	Field control system	La-M controller LF-Control control system, including cabinet, control core, real-time control software, signal acquisition, frequency converter, power drive, switch master, man-machine touch screen display, etc. Control core: Siemens S7-200 series programmable controller; 10-inch true color touch screen.	XIANGYI
8	Governor	Governor	QR
9	Rotameter	Flow rate: 50L/min	Changzhou
10	Intake and exhaust fine filter	0.01μm	Shanghai
11	Feeding peristaltic pump	0~55ml\min	Baoding
12	Defoaming peristaltic pump	0~55ml\min	Baoding
13	Acid supplement peristaltic pump	0~55ml\min	Baoding
14	Alkali peristaltic pump	0~55ml\min	Baoding
15	Circulation pump	Grund fos/Ville	Denmark/Germany
16	pH electrode	Mettler	Switzerland
17	pH cable	Mettler	Switzerland
18	DO electrode	Mettler	Switzerland
19	DO cable	Mettler	Switzerland
20	jacket	ZGL-25BT-200	QR
21	Temperature electrode	PT100	Japan
22	Cooling water control valve	Yongchuang	Zhejiang
23	Diaphragm valve	Hebron	Shanghai
24	Piping system, supporting accessories	Pipelines, pipe racks, water valves, air valves, steam valves, safety valves, pressure gauges, sealing rings, clamps, connectors, etc., hoses, silicone tubes, pins, plugs, special tools.	XIANGYI

Standard spare parts

No.	Item Name	Specific	Qty
1	Blue cover high temperature refill bottle (glass)	250ml	3 pcs
2	Lan cover high temperature refill bottle (glass)	500ml	1 pc
3	Refill bottle accessories	Fit	4 set
4	Dedicated replenishment pin (with jacket)	3 needles	1 pc
5	Dedicated replenishment pin (with jacket)	1 needles	1 pc
6	High quality sanitary refill silicone tube	16#	8 m
7	High-quality sanitary refill silicone tube	25#	8 m
8	Simple tools and toolbox		1 pc
9	Spare sealing O-ring	Connector	10 set
10	Special silicone plug		10 pcs
11	Sterilization filter 0.1μm (imported from Germany)	φ25mm	4 pcs

Paddle type (Optional)

No.	Type	Description
1	Paddle	The basic structure of paddle agitator generally consists of four parts: paddle, key, collar and vertical shaft. Commonly used blades are generally made of ordinary flat steel or angle steel. When the stirred medium is corrosive to steel, the material used is stainless steel.
2	Back curved blade disc turboprop	Compared with the turbine type agitator, this type of agitator has the same basic flow pattern, and also has high shear capacity and larger circulation capacity. The difference is that there is one more disk, and some gas can be stored underneath to make the gas dispersion more stable. It is suitable for use in the process of gas dispersion absorption; the curved blade has a back angle, good discharge performance, and low power consumption.
3	Semicircular tube disc turboprop	Radial flow agitators, their blades are concave arc-shaped, with extremely strong radial displacement and dispersion ability, under the same power, its mass transfer coefficient is more than 20% higher than that of the flat blade disc turbine, and its air holding capacity Increased by more than 30%, and the power consumption is relatively low, so it is especially suitable for the dissolved oxygen operation reaction similar to the fermentation process, and also suitable for other operations such as gas dispersion, absorption and mixing, mass transfer and heat transfer.
4	Parabolic disc turboprop	Radial flow agitators, their blades are parabolic, have extremely strong radial displacement and dispersion ability, under the same power, its mass transfer coefficient is more than 30% higher than that of the flat blade disc turbine, and the air holding capacity is increased by more than 40% , And the power consumption ratio is very low, so it is especially suitable for the dissolved oxygen operation similar to the fermentation process, and it is also suitable for gas dispersion, absorption, mass transfer and heat transfer under other requirements.
5	Turboprop	This type of agitator draws on the development and development of advanced foreign similar products. Compared with the curved blade disc turbine type agitator, the basic flow pattern is the same, and it also has high shear capacity and greater circulation capacity. The difference is that it is larger in size and more than two. Only the disc is closed, a large amount of gas can be stored below, and the gas and liquid dispersion downward is more stable, and at the same time, higher speed is not required, so it is more suitable in the gas dispersion and absorption process. The paddle can be made into a detachable paddle to facilitate installation and maintenance.
6	Propeller	The three-blade propeller is the most typical axial flow type agitator, with high discharge capacity and low shear performance: the use of baffles or guide tubes will enhance the axial circulation and significantly improve the discharge performance because of its strong circulation and power Low consumption can best reflect its advantages when used in large-capacity homogeneous and mixing processes. It is widely used in low-viscosity liquid heat transfer, reaction, suspension and dissolution with a small solid-to-liquid ratio.
7	Anchor paddle	This type of agitator is a slow-speed agitator, suitable for the mixing, heat transfer or reaction process of medium and high viscosity liquids. The rotating surface of the paddle bottom is close to the elliptical surface of the container, and it also acts as a scraper. It mostly runs at low speed and often operates in laminar flow. Produce horizontal circular flow, such as hinged blade or angle steel blade, can increase the vortex near the blade.
8	Anchor frame paddle	This type of agitator is a slow-speed agitator, suitable for the mixing, heat transfer or reaction process of medium and high viscosity liquids. Often operate in laminar flow. Produce horizontal circular flow, such as hinged blade or angle steel blade, can increase the vortex near the blade. You can add vertical blades and beams on the paddle as needed to increase the mixing range.
9	Screw propeller	This type of agitator is a slow-speed agitator. It is often operated in the laminar flow zone. The liquid rises or falls along the spiral surface to form an axial upward and downward circulation. It is suitable for the mixing and heat transfer of medium and high viscosity liquids. The spiral ribbon profile of the spiral ribbon stirrer is close to the inner wall of the stirring tank, and the stirring diameter is large, which strengthens the up and down circulation of the liquid near the tank wall. The heat transfer process of the high viscosity liquid is very suitable. The screw-belt screw combination type has the characteristics of screw and spiral at the same time, which strengthens the circulation of the inner and outer liquids, and is especially effective for non-Newtonian plastic and viscoelastic liquids. It can be designed according to the shape of the bottom of the kettle.
10	Brumakin Paddle	A six-blade turbine type modified agitator. Radial flow pattern, the front end of the blade is widened and there is a back curve, which not only improves the discharge performance, but also reduces the shear strength. The power consumption is less, and the discharge performance is better than the straight blade or the curved blade opening turbine. When there is a baffle, it can form up and down circulation flow, which is more suitable for mixing, dispersion, solid-liquid suspension, dissolution and other processes.
11	Three-blade swept propeller	The radial flow agitator, combined with the finger-shaped baffle, can obtain a large flow of up and down circulation, and has good shearing effect. It is suitable for heat transfer, mass transfer, solid dissolution, solid-liquid suspension, polymerization, etc.

After-sales service commitment
XIANGYI INSTRUMENTS is committed to providing professional equipment and services in the field of bioengineering. In order to create a new generation of fermenters, XIANGYI will provide the most comprehensive after-sales service system in the industry. Here we promise:

1) Free after-sales service for the following year: After the acceptance of the equipment, from the acceptance date of the acceptance, it promises to provide free warranty for the equipment for the next year (except human factors) for lifetime maintenance. If the inspection is not carried out within 30 days after arrival, the free warranty time will be calculated from the 30th day after the arrival.
2) Lifetime software upgrade support: XIANGYI is committed to providing the best after-sales service, including our constantly improving software system, we will provide software upgrade service for users in 1~2 years according to the maturity of product software.
3) Timely response service: XIANGYI adopts multi-level technical response method and provides product technical support. Our continuous improvement of dealer system in the country will provide users with reliable product after-sales support. Customers can also directly contact our after-sales service engineers, after-sales service engineers will give you timely after-sales response support within 24 hours.
4) After the insurance, product support: a, consumables: due to the defects of consumables itself, XIANGYI is responsible for free replacement. Standard consumables can be purchased by themselves or purchased by XIANGYI. b. After the warranty period: The standard parts will be provided by XIANGYI, which will be supplied all the year round to ensure the quick response of the purchase. At the same time, we only charge the basic production cost of the customer parts.

PRODUCT PICTURE